Effect of Okra Fruit (Abelmoschus esculentus) Extract on Granzyme Expression and Tumor Mass Diameter of Adenocarcinoma Mammae: An In Vivo Study

Background: Breast cancer is currently one of the most common types suffered by women, with highest prevalence in all countries world. Herbal plants are thought to increase immune system against tumors, which okra (Abelmoschus esculentus) has potential as an anti-tumor and anti-carcinogenic. This study aimed assess efficacy ethanol extract on granzyme expression tumor mass diameter mammary adenocarcinoma rats treated adriamycin-cyclophosphamide chemotherapy.
 Methods: experimental using 28 Sprague Dawley Rats. Data analysis was performed SPSS version 21 differences size.
 Results: The combination chemotherapy fruit (P3) showed optimal increasing reducing Conclusion: treatment carcinoma granzymes so reduce size breast tumors vivo.